brain biomedical image

The use of microendoscopes to diagnose internal problems is not new, but the technology has been constantly advancing – and may be about to take another leap forward.

Using fibre optics, the devices have been able to produce biomedical images from all manner of locations inside the human body that would not have been possible decades ago, making possible diagnostics that previously would have been impossible without invasive exploratory surgery. 

This can be extremely useful and, combined with cloud medical image storage, can leverage the best modern technology to ensure image-based diagnostics can provide the right information to medical professionals, wherever and whenever they need it.

However, the International Centre for Translational Eye Research (ICTER) notes, the technology has its limitations in terms of how clear the images are that can be produced. 

For this reason, staff at ICTER have been working on developing better microendoscopes, with a new paper jointly published by ICTER’s professor Karol Karnowski and colleagues at universities in Denmark and Australia outlining how imaging can be improved by using endoscopic imaging probes that combine fibre optics with spherical lenses.

This combination helps produce a wider range of high quality images that can be applicable across a wider range of applications than existing fibre optic technology. The researchers concluded that the performance level of endoscopic imaging probes is on a similar level to the single focusing element probes commonly used at present.

It is not only in the field of microendoscopy that imaging technology is advancing. The South Australian Health and Medical Research Institute in Adelaide has unveiled new scanner technology that can look inside coronary arteries and enhance the study of cancer cells, 7 News reports.

The full-body photon-counting computed tomography machine is the first one of its kind in Australia, and has been hailed as the biggest advance in CT imaging technology in 20 years by the institute’s head of imaging Andrew Dwyer.

 

 

New MRI scans that use 4D images have been developed to be able to diagnose heart failure in just eight minutes. 

Researchers from the University of East Anglia (UEA) have created technology that uses magnetic response imaging (MRI) to take 4D images of heart valves and blood flow. This has helped reduce diagnostic times from 20 minutes to just eight.

PhD student Hosamadin Assadi, from UEA’s Norwich Medical School, said: “This new technology is revolutionising how patients with heart disease are diagnosed.”

He explained the university teamed up with General Electric Healthcare to determine how reliable a new technique called Kat-ARC is as a diagnostic tool. It was found the scans not only reduce the amount of time it takes to get accurate pictures of the heart, but also measure the peak velocity of blood flow in the heart. 

Lead researcher Dr Pankaj Garg, also from Norwich Medical School, stated the best way to diagnose heart failure is through an invasive assessment, or by ultrasound scan, which can be unreliable. 

The 4D imaging, however, can look at the flow of blood in three directions over time, providing detailed information about the condition of the organ. 

Dr Garg stated if the 4D MRIs become commonplace, “this will benefit hospitals and patients across the whole world”.   

Causes of heart failure include high blood pressure, cardiomyopathy, a heart attack, congenital heart conditions, heart valve disease, and abnormal heart rhythms. 

According to the NHS, heart failure impacts 900,000 people in the UK, with 60,000 new cases emerging every year. 

 

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A major research pathway in the world of medical imaging is in the field of artificial intelligence and machine learning, which are used to help doctors identify cell samples that potentially show signs of cancer.

There is a range of systems available, each rapidly evolving as AI permeates into many facets of life and evolves to meet the needs of various industries.

However, the earliest and most incredible example of this is how a system designed to scan for freshly baked bread and pastries became a major tool in some hospitals to help doctors efficiently scan for cancer in cell samples.

For context, Japanese bakeries do not sell packaged bread products, because bread in the open looks fresher and more appealing.

With these bakeries expanding their product ranges dramatically, it was getting increasingly difficult for customer service staff to efficiently serve customers as they needed to memorise a lot of different pastry types.

In 2007, a lot of scanning systems relied on barcodes or used somewhat rudimentary AI recognition technology that typically could only recognise standardised shapes and designs, which given that baking is not always consistent, led to confusion.

Enter BakeryScan, an advanced AI scanning system that could be trained to accurately detect different types of bread, work out when a pastry had ripped or was two separate items, could detect different bread items touching and was heralded for its accuracy by the baking world.

However, a decade later, a doctor based at the Louis Pasteur Centre for Medical Research in Kyoto had a brilliant idea. As cancer cells could in some cases look similar to these pastry products, a custom baking scanner could be used to efficiently look for cancer cells.

This led to the development of Cyto-AiSCAN, which uses the same technology to analyse an entire slide of cells with an accuracy level of 99 per cent, allowing for quicker cancer diagnoses and potentially saving countless lives in the process.

There are many kinds of medical imaging used today, but what is medical imaging and how does it work?

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The NHS is trying to reduce waiting times for patients by introducing artificial intelligence (AI) tools called ChatBot. 

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After decades of studies and speculations, medical imaging research has shown the effects that medications containing steroids can have on the brain.

The study, published in the British Medical Journal, found that there was a connection between steroid use and reduced white matter integrity, and this could have major implications for long-term prescriptions of steroid medication.

In the brain, the white matter is the densely packed bundles of nerve fibres that work to coordinate the different brain regions and have a major effect on brain functions and learning, and so decreased integrity can have notable neuropsychiatric effects.

The study noted that people who regularly use glucocorticoid, a steroid commonly used in inhalers to help mitigate asthma symptoms, would appear to be more restless, lethargic, disinterested and show depressive symptoms compared to people who do not use them or only occasionally inhale them.

This study helps to confirm and clarify the reasons why steroids can have a strong effect on mental health, particularly for long-term users and steroid abusers.

Historically, steroid users have commented on a range of different mental health effects, including depression, mania, increased impulsive behaviour, increased aggression (that would sometimes manifest in “roid-rage” outbursts, increased anxiety, paranoia and psychosis.

As well as this, some steroid users reported feeling addicted or psychologically dependent on them, partly due to neuropsychiatric factors but also due to their perceived effects.

Specifically, glucocorticoids are amongst the most widely prescribed anti-inflammatories on the market and are used not only to treat asthma but also Crohn’s Disease, eczema, lupus, tendinitis, multiple sclerosis, allergies and arthritis.

It should be noted that these steroids are only used in certain types of prescribed inhalers, rather than the rescue inhalers commonly used to immediately open an airway during an asthma attack and use muscle relaxing medication.

More research is required, and no dramatic action should be taken yet, as other studies need to show how long the reported effects can last and whether they are permanent.

After decades of studies and speculations, medical imaging research has shown the effects that medications containing steroids can have on the brain.

The study, published in the British Medical Journal, found that there was a connection between steroid use and reduced white matter integrity, and this could have major implications for long-term prescriptions of steroid medication.

In the brain, the white matter is the densely packed bundles of nerve fibres that work to coordinate the different brain regions and have a major effect on brain functions and learning, and so decreased integrity can have notable neuropsychiatric effects.

The study noted that people who regularly use glucocorticoid, a steroid commonly used in inhalers to help mitigate asthma symptoms, would appear to be more restless, lethargic, disinterested and show depressive symptoms compared to people who do not use them or only occasionally inhale them.

This study helps to confirm and clarify the reasons why steroids can have a strong effect on mental health, particularly for long-term users and steroid abusers.

Historically, steroid users have commented on a range of different mental health effects, including depression, mania, increased impulsive behaviour, increased aggression (that would sometimes manifest in “roid-rage” outbursts, increased anxiety, paranoia and psychosis.

As well as this, some steroid users reported feeling addicted or psychologically dependent on them, partly due to neuropsychiatric factors but also due to their perceived effects.

Specifically, glucocorticoids are amongst the most widely prescribed anti-inflammatories on the market and are used not only to treat asthma but also Crohn’s Disease, eczema, lupus, tendinitis, multiple sclerosis, allergies and arthritis.

It should be noted that these steroids are only used in certain types of prescribed inhalers, rather than the rescue inhalers commonly used to immediately open an airway during an asthma attack and use muscle relaxing medication.

More research is required, and no dramatic action should be taken yet, as other studies need to show how long the reported effects can last and whether they are permanent.

Scans can have all kinds of medical benefits in diagnostics – but sometimes these can be unexpected.

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The Institute of Cancer Research has shortlisted five pictures taken using medical imaging equipment to highlight the wide range of striking discoveries found using state-of-the-art diagnostic technology.

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Scientists have created artificial intelligence (AI) that can remove large kidney stones.

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